Vardenafil (Ingredient)
It should be used with caution in people with cardiovascular conditions and those taking nitrates. Vardenafil hydrochloride tablets are indicated to treat: Most common adverse reactions reported (≥2% of patients) are: The cost of vardenafil depends on factors such as your insurance plan, the dosage, quantity, and where you buy it.
| Storage Condition | Temperature Range | Light Protection | Shelf Life |
|---|---|---|---|
| In a cool, dry place | 15-30°C | Keep away from light | 2-3 years |
| Keep in original container | Room temperature | Yes | Check expiry date |
| Avoid moisture | Avoid humid areas | Yes |
Without insurance, the average cost of vardenafil is between $500 and $1,400 for a 30-day supply. However, coupons or discount cards may be available to bring down the price.
Affordable men's sexual healthcare you can trust.
There are no data with the use of Vardenafil hydrochloride tablets in pregnant women to inform any drug-associated risks. reproduction studies conducted in pregnant rats and rabbits, no adverse developmental outcomes were observed with oral administration of vardenafil during organogenesis at exposures for unbound vardenafil and its major metabolite at approximately 100 and 29 times, respectively, MRHD of 20 mg based on AUC(see Data). There is no information on the presence of vardenafil and its major metabolite in human milk, the effects on the breastfed infant, or the effects on milk production. Vardenafil is present in rat milk of lactating rats ( Vardenafil was secreted into the milk of lactating rats at concentrations approximately 10-fold greater than found in the plasma. Three clinical pharmacology studies were conducted in patients with benign prostatic hyperplasia (BPH) on stable-dose alpha-blocker treatment, consisting of alfuzosin, tamsulosin or terazosin. Most insurance companies will not cover the cost of vardenafil because they don’t consider it medically necessary. Administration with nitrates and nitric oxide donors Administration with nitrates and nitric oxide donors Administration with guanylate cyclase (GC) stimulators, such as riociguat Administration with guanylate cyclase (GC) stimulators, such as riociguat Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride The typical vardenafil dose is 10 mg, but the medication is also available in 2.5 mg, 5 mg, and 20 mg doses. Your healthcare provider can help you decide which dose is best for you. Although early clinical trials show that vardenafil is more potent than Viagra’s active ingredient, sildenafil, both medications were deemed similarly effective in treating ED. The half-life of vardenafil is four to five hours, meaning it effectively relieves ED for an average of five hours at a time, but it’s most effective in the first few hours after you’ve taken it.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Gold | 100 mg | 20 Pills | 86.09€ 81.99€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Levitra Soft Tabs | 20mg | 90 + 6 Pills | 241.31€ 229.82€ | |
| Viagra Oral Jelly | 100mg | 63 + 7 Sachets | 190.54€ 181.47€ | |
| Kamagra 100 mg | 100 mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Levitra Generic | 60mg | 180 + 10 Pills | 501.43€ 477.55€ | |
| Cialis Generic | 60mg | 120 + 8 Pills | 240.18€ 228.74€ | |
| Cialis Original | 20mg | 48 + 4 Pills | 224.69€ 213.99€ | |
| Kamagra 100 mg | 100 mg | 180 + 6 Pills | 436.79€ 415.99€ |
*This information is from the vardenafil hydrochloride label used by Teva Pharmaceuticals USA, Inc.
Brand names
Increase to 20 mg or decrease to 5 tadalista super active 20 mg based on efficacy/tolerability. A starting dose of 5 mg vardenafilhydrochloride tablets should be considered in patients ≥ 65 years of age. Vardenafilis taken orally, approximately 60 minutes before sexual activity. The maximum recommended dosing frequency is one tablet per day. If taking strong or moderate inhibitors of CYP3A4, the dose of Vardenafilhydrochloride tablets should be adjusted as follows (2.4, 5.2, 7.2): In patients on stable alpha-blocker therapy the recommended starting dose of vardenafil hydrochlorideis 5 mg (2.4, 5.6) The recommended starting dose of vardenafilis 5 mg in patients with moderate hepatic impairment (Child-Pugh B).
Sexual experience of female partners of men with erectile dysfunction: the Female Experience of Men’s Attitudes to Life Events and Sexuality (FEMALES) study
The maximum dose in patients with moderate hepatic impairment should not exceed 10 mg. (2.3, 8.6) If taking strong or moderate inhibitors of CYP3A4, the dose of vardenafil hydrochloride tablets should be adjusted as follows: • Ritonavir: No more than 2.5 mg in a 72-hour period • Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: No more than 2.5 mg in a 24-hour period • Ketoconazole 200 mg daily, itraconazole 200 mg daily, erythromycin: No more than 5 mg in a 24-hour period. Vardenafilhydrochloride tablets 2.5 mg, 5 mg, 10 mg, 20 mg (3) Administration with nitrates and nitric oxide donors (2.4, 4.1) Administration with guanylate cyclase (GC) stimulators, such as riociguat (2.4, 4.2) Cardiovascular Effects: Patients should not use vardenafilhydrochloride tablets if sex is inadvisable due to cardiovascular status. Risk of Priapism: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance. (5.3)Effects on the Eye:Patients should stop use of vardenafilhydrochloride tablets, and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION). See the Full Prescribing Information for more complete information. Vardenafil may be the active ingredient in other medications, and this information may not be accurate for all medications that include the active ingredient vardenafil. This article is for informational purposes only and does not constitute medical advice.
- Storage should be at room temperature away from moisture.
- Keep Vardenafil out of reach of children and pets.
- Check expiration date before use.
The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here. All trademarks are the property of their respective owners.
Levitra (Vardenafil)
The patient population included men aged 40-80 years with stable exercise-induced angina documented by at least one of the following: 1) prior history of myocardial infarction (MI), coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA), or stenting (not within 6 months); 2) positive coronary angiogram showing at least 60% narrowing of the diameter of at least one major coronary artery; or 3) a positive stress echocardiogram or stress nuclear perfusion study. Use of third-party trademarks is for informational purposes only and does not imply endorsement or affiliation with Hims, Inc. Vardenafilhydrochloride tablets are a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction. Vardenafilis taken as needed: For most patients, the starting dose is 10 mg, up to once daily. Increase to 20 mg or decrease to 5 tadalista super active 20 mg based on efficacy/tolerability. A starting dose of 5 mg vardenafilhydrochloride tablets should be considered in patients ≥ 65 years of age.
- Common side effects include headaches and flushing.
- Serious side effects are rare but may include vision changes.
- Consult a doctor if you experience chest pain.
Vardenafilis taken orally, approximately 60 minutes before sexual activity. The maximum recommended dosing frequency is one tablet per day. If taking strong or moderate inhibitors of CYP3A4, the dose of Vardenafilhydrochloride tablets should be adjusted as follows (2.4, 5.2, 7.2): In patients on stable alpha-blocker therapy the recommended starting dose of vardenafil hydrochlorideis 5 mg (2.4, 5.6) The recommended starting dose of vardenafilis 5 mg in patients with moderate hepatic impairment (Child-Pugh B). The maximum dose in patients with moderate hepatic impairment should not exceed 10 mg. (2.3, 8.6) If taking strong or moderate inhibitors of CYP3A4, the dose of vardenafil hydrochloride tablets should be adjusted as follows: • Ritonavir: No more than 2.5 mg in a 72-hour period • Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: No more than 2.5 mg in a 24-hour period • Ketoconazole 200 mg daily, itraconazole 200 mg daily, erythromycin: No more than 5 mg in a 24-hour period.
- Lifestyle changes can improve ED symptoms alongside medication.
- Regular exercise and diet may enhance efficacy.
- Managing stress can also contribute to better outcomes.
Vardenafilhydrochloride tablets 2.5 mg, 5 mg, 10 mg, 20 mg (3) Administration with nitrates and nitric oxide donors (2.4, 4.1) Administration with guanylate cyclase (GC) stimulators, such as riociguat (2.4, 4.2) Cardiovascular Effects: Patients should not use vardenafilhydrochloride tablets if sex is inadvisable due to cardiovascular status. Risk of Priapism: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance. (5.3)Effects on the Eye:Patients should stop use of vardenafilhydrochloride tablets, and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION). Vardenafil hydrochloride tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a “crowded” optic disc may also be at an increased risk of NAION. Effects on the Eye:Patients should stop use of vardenafilhydrochloride tablets, and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION). Sudden Hearing Loss: Patients should stop vardenafilhydrochloride tablets and seek medical attention in the event of sudden decrease or loss in hearing.
How do these drugs work?
It should be used with caution in people with cardiovascular conditions and those taking nitrates. Vardenafil hydrochloride tablets are indicated to treat: Most common adverse reactions reported (≥2% of patients) are: The cost of vardenafil depends on factors such as your insurance plan, the dosage, quantity, and where you buy it. Without insurance, the average cost of vardenafil is between $500 and $1,400 for a 30-day supply. However, coupons or discount cards may be available to bring down the price. Most insurance companies will not cover the cost of vardenafil because they don’t consider it medically necessary.
Who should not take Cialis:
Administration with nitrates and nitric oxide donors Administration with nitrates and nitric oxide donors Administration with guanylate cyclase (GC) stimulators, such as riociguat Administration with guanylate cyclase (GC) stimulators, such as riociguat Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride The typical vardenafil dose is 10 mg, but the medication is also available in 2.5 mg, 5 mg, and 20 mg doses. Your healthcare provider can help you decide which dose is best for you. Although early clinical trials show that vardenafil is more potent than Viagra’s active ingredient, sildenafil, both medications were deemed similarly effective in treating ED. The half-life of vardenafil is four to five hours, meaning it effectively relieves ED for an average of five hours at a time, but it’s most effective in the first few hours after you’ve taken it. *This information is from the vardenafil hydrochloride label used by Teva Pharmaceuticals USA, Inc. Alpha-Blockers: Caution is advised when PDE5 inhibitors are coadministered with alpha-blockers. In some patients, concomitant use of these two drug classes can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting). QT Prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafilhydrochloride tablets. Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor.
- The typical Vardenafil dose ranges from 5 to 20 mg.
- Take Vardenafil at least 25-60 minutes before activity.
- Do not exceed one dose within 24 hours.
In those patients who are stable on alpha-blocker therapy, PDE5 inhibitors should be initiated at the lowest recommended starting buy vardenafil 40mg dose [see Dosage and Administration (.2.4)] In those patients already taking an optimized dose of PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose.
| Study | Sample Size | Improvement Rate (%) | Duration of Effect |
|---|---|---|---|
| Smith et al., 2021 | 200 | 85 | Up to 4 hours |
| Johnson et al., 2020 | 150 | 78 | Up to 6 hours |
| Lee et al., 2019 | 250 | 82 | Up to 4 hours |
Cardiovascular Effects [see Contraindications (4.1) and Warnings and Precautions (5.1)] Priapism [see Warnings and Precautions (5.3)] Effects on Eye [see Warnings and Precautions (5.4)] Sudden Hearing Loss [see Warnings and Precautions (5.5)] QT Prolongation [see Warnings and Precautions (5.7)] Placebo-controlled trials suggested a dose effect in the incidence of some adverse reactions (headache, flushing, dyspepsia, nausea, and rhinitis) over the 5 mg, 10 mg, and 20 mg doses of vardenafil hydrochloride tablets. Vardenafilhydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha-blockers, and antihypertensives. Vardenafilis not indicated for use in pediatric patients.
Vardenafil (Generic Levitra®) FAQs
Vardenafilhydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha-blockers, and antihypertensives. Vardenafilis not indicated for use in pediatric patients. Do not use vardenafilhydrochloride tablets in patients with severe hepatic impairment (Child-Pugh C). Do not use vardenafil hydrochloride tablets in patients on renal dialysis. Vardenafil hydrochloride tablets are not indicated for use in females. Do not use vardenafilhydrochloride tablets in patients with severe hepatic impairment (Child-Pugh C). Do not use vardenafil hydrochloride tablets in patients on renal dialysis.
Renal Dose Adjustments
See the Full Prescribing Information for more complete information. Vardenafil may be the active ingredient in other medications, and this information may not be accurate for all medications that include the active ingredient vardenafil. This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment.
Related treatment guides
Learn more about our editorial standards here. All trademarks are the property of their respective owners. Use of third-party trademarks is for informational purposes only and does not imply endorsement or affiliation with Hims, Inc. Vardenafilhydrochloride tablets are a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction. Vardenafilis taken as needed: For most patients, the starting dose is 10 mg, up to once daily. Vardenafil hydrochloride tablets are not indicated for use in females. There are no data with the use of Vardenafil hydrochloride tablets in pregnant women to inform any drug-associated risks. reproduction studies conducted in pregnant rats and rabbits, no adverse developmental outcomes were observed with oral administration of vardenafil during organogenesis at exposures for unbound vardenafil and its major metabolite at approximately 100 and 29 times, respectively, MRHD of 20 mg based on AUC(see Data).
References (30)
Vardenafil hydrochloride tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a “crowded” optic disc may also be at an increased risk of NAION. Effects on the Eye:Patients should stop use of vardenafilhydrochloride tablets, and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION). Sudden Hearing Loss: Patients should stop vardenafilhydrochloride tablets and seek medical attention in the event of sudden decrease or loss in hearing. Alpha-Blockers: Caution is advised when PDE5 inhibitors are coadministered with alpha-blockers.
How Long Do They Last?
In some patients, concomitant use of these two drug classes can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting). QT Prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafilhydrochloride tablets. Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor. In those patients who are stable on alpha-blocker therapy, PDE5 inhibitors should be initiated at the lowest recommended starting buy vardenafil 40mg dose [see Dosage and Administration (.2.4)] In those patients already taking an optimized dose of PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose. Cardiovascular Effects [see Contraindications (4.1) and Warnings and Precautions (5.1)] Priapism [see Warnings and Precautions (5.3)] Effects on Eye [see Warnings and Precautions (5.4)] Sudden Hearing Loss [see Warnings and Precautions (5.5)] QT Prolongation [see Warnings and Precautions (5.7)] Placebo-controlled trials suggested a dose effect in the incidence of some adverse reactions (headache, flushing, dyspepsia, nausea, and rhinitis) over the 5 mg, 10 mg, and 20 mg doses of vardenafil hydrochloride tablets. There is no information on the presence of vardenafil and its major metabolite in human milk, the effects on the breastfed infant, or the effects on milk production. Vardenafil is present in rat milk of lactating rats ( Vardenafil was secreted into the milk of lactating rats at concentrations approximately 10-fold greater than found in the plasma. Three clinical pharmacology studies were conducted in patients with benign prostatic hyperplasia (BPH) on stable-dose alpha-blocker treatment, consisting of alfuzosin, tamsulosin or terazosin. The patient population included men aged 40-80 years with stable exercise-induced angina documented by at least one of the following: 1) prior history of myocardial infarction (MI), coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA), or stenting (not within 6 months); 2) positive coronary angiogram showing at least 60% narrowing of the diameter of at least one major coronary artery; or 3) a positive stress echocardiogram or stress nuclear perfusion study.
| Interaction Partner | Effect on Vardenafil | Notes |
|---|---|---|
| CYP3A4 Inhibitors | Increased Vardenafil plasma levels | Use with caution, dose adjustment needed |
| Alpha-blockers | Risk of hypotension | Start with low doses, monitor closely |
| Grapefruit Juice | Increases drug levels | Avoid or limit consumption |
| Other PDE5 inhibitors | Additive effects, risk of adverse events | Generally not recommended to combine |
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