Sildenafil/Tadalafil 55mg/12.5mg Oral Disintegrating Tablet (ODT) (Quantity: 1)
Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors.
5.4 Visual Loss
Do not take sildenafil if you are using medications called nitrates, such as nitroglycerin, or over-the-counter nitrites (“poppers”), such as amyl nitrite. Sildenafil should also never be combined with heart failure drugs called guanylate cyclase stimulators (riociguat or vericiguat). Make sure the prescriber knows about all drugs and substances you use, including vitamins, supplements, and illicit substances. To avoid more serious drug interactions, the prescriber will need to know about: Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil HIV/AIDS drugs called protease inhibitors, especially ritonavir HIV/AIDS drugs called protease inhibitors, especially ritonavir Oral antifungal drugs such as ketoconazole or itraconazole Oral antifungal drugs such as ketoconazole or itraconazole To reduce the risk of side effects, avoid drinking grapefruit juice when taking sildenafil. Although there isn’t much information about the safety of sildenafil during pregnancy, animal studies have shown no adverse effects on a fetus.
What’s the difference between sildenafil 50 mg and 100 mg?
Pregnant women or women who are breastfeeding should ask for medical advice before taking sildenafil. Plumb’s Veterinary Drug Manual, 7 edition Plumb’s Veterinary Drug Manual, 7 edition Revatio prescribing information, DailyMed (NIH National Library of Medicine) Revatio prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist. She currently resides in Pennsylvania and works as a community pharmacist. She is also a freelance medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family. Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil).
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Kamagra | 100mg | 12 Pills | 55.64€ 52.99€ | |
| Viagra Generic | 25mg | 120 + 6 Pills | 125.56€ 119.58€ | |
| Viagra Generic | 25mg | 10 Pills | 25.19€ 23.99€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 25mg | 270 + 8 Pills | 184.26€ 175.49€ | |
| Kamagra Oral Jelly | 100mg | 63 + 7 Sachets | 224.18€ 213.50€ | |
| Kamagra Oral Jelly | 100mg | 21 Sachets | 95.92€ 91.35€ |
However, due to Viatris Specialty LLC's marketing exclusivity rights, this drug product is not labeled with that information.
Additional information
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Adjusting Your Sildenafil Dosage Over Time
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Table of Contents FULL PRESCRIBING INFORMATION: CONTENTS*1 INDICATIONS AND USAGE2 DOSAGE AND ADMINISTRATION2.1 Recommended
Related/similar drugs
Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays).
Competing interests
Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. If you are a consumer or patient please visit this version. Dosage in Adults3 DOSAGE FORMS AND STRENGTHS4
| Medication Type | Interaction Effect | Recommended Action |
|---|---|---|
| Nitrates | Severe hypotension | Avoid concurrent use |
| Alpha-blockers | Blood pressure lowering effects | Monitor blood pressure closely |
| CYP3A4 inhibitors | Increased sildenafil levels, risk of side effects | Dose adjustment or caution |
| Other PDE5 inhibitors | Enhanced effects, risk of adverse reactions | Avoid combination |
CONTRAINDICATIONS5 WARNINGS AND PRECAUTIONS5.1 Hypotension5.2 Worsening Pulmonary Vascular
| Study Name | Sample Size | Success Rate | Main Findings |
|---|---|---|---|
| Randomized Trial A | 200 | 70% | Significant improvement in erectile function |
| Clinical Study B | 150 | 65% | Efficacy maintained at 12.5 mg dose |
| Comparative Study C | 100 | 75% | Similar results to higher doses but fewer side effects |
Occlusive Disease5.3 Epistaxis5.4 Visual Loss5.5 Hearing Loss5.6 Combination with other PDE-5 Inhibitors5.7 Priapism5.8 Vaso-occlusive Crisis in Patients with Pulmonary Hypertension Secondary to Sickle Cell Disease6 ADVERSE REACTIONS6.1 Clinical Trials
- Sildenafil 12.5 mg is a lower dose used for mild erectile dysfunction.
- It helps relax blood vessels to increase blood flow.
- Often prescribed when starting treatment or for lighter symptoms.
Experience6.2 Postmarketing Experience7 DRUG INTERACTIONS8 USE IN
| Country | Legal Status | Can be OTC? | Prescription Required? |
|---|---|---|---|
| United States | Prescription only | No | Yes |
| European Union | Prescription required | No | Yes |
| India | Available OTC in some locations | Yes | No |
| Australia | Prescription required | No | Yes |
SPECIFIC POPULATIONS8.1 Pregnancy8.2 Lactation8.4 Pediatric Use8.5 Geriatric
- This dose is often used as a starting point before increasing if needed.
- Combining with high-fat meals may slow absorption.
- Avoid grapefruit juice, as it can affect sildenafil metabolism.
Use8.6 Patients with Hepatic Impairment8.7 Patients with
8.6 Patients with Hepatic Impairment
With a half-life of four hours, sildenafil and its active metabolite are completely cleared from the system in about 20 hours, though the effects fade before then. For erectile dysfunction, sildenafil produces its maximum effects for about two hours and can still produce an erectile response four hours after a dose is taken. For pulmonary hypertension, sildenafil’s benefits in lowering blood pressure were the same as a placebo (inert pill) after eight hours. For treatment of erectile dysfunction, take only one dose per day. If a dose has been forgotten, take it when remembered but wait at least 30 minutes before attempting sexual activity.
Alcohol interaction warning
For pulmonary hypertension, take a missed dose as soon as you remember it. If it’s almost time for the next dose, skip the missed dose and take the next dose as scheduled. If too much sildenafil is taken, get immediate medical attention. Side effects of sildenafil, such as headache, flushing, stomach upset, nasal congestion, back pain, low blood pressure, or painful erections (priapism), are more likely and could be worse than normal. Serious side effects are also possible such as heart rate problems, chest pain (angina), and heart attack. Renal Impairment10 OVERDOSAGE11 DESCRIPTION12 CLINICAL PHARMACOLOGY12.1 Mechanism of
- Sildenafil 12.5 mg is contraindicated with nitrate medications.
- Alcohol can reduce effectiveness and increase side effect risk.
- Always follow your healthcare provider’s dosage instructions carefully.
Action12.2 Pharmacodynamics12.3 Pharmacokinetics13 NONCLINICAL TOXICOLOGY13.1 Carcinogenesis, Mutagenesis,
METHODS AND RESULTS
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL INJECTION safely and effectively. See full prescribing information for SILDENAFIL INJECTION.SILDENAFIL injection, for intravenous useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil injection is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health sildenafil citrate 200mg price Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1)DOSAGE AND ADMINISTRATIONInjection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1)DOSAGE FORMS AND STRENGTHSInjection: 10 mg/12.5 mL in a single-dose vial (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended.
Is 20 mg of sildenafil effective for ED?
(5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. (7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. (5.6)Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil). Impairment of Fertility14 CLINICAL STUDIES16 HOW SUPPLIED/STORAGE AND
More about sildenafil
However, due to Viatris Specialty LLC's marketing exclusivity rights, this drug product is not labeled with that information.See 17 for PATIENT COUNSELING INFORMATION.Revised: 12/2023 Injection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1) Injection: 10 mg/12.5 mL in a single-dose vial (3) Vasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises. Use with strong CYP3A inhibitors: Not recommended. HANDLING17 PATIENT COUNSELING INFORMATION*Sections or subsections omitted from the full prescribing information are not listed.
- Store sildenafil at room temperature, away from moisture and heat.
- Keep out of reach of children and pets.
- Do not use expired medication; freshness ensures safety and efficacy.
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